two.four mya with the emergence of A. microta.[sixty][61] Genome sequencing of the large panda implies that the dietary change might have initiated in the lack of the only real umami taste receptor, encoded with the genes TAS1R1 and TAS1R3 (also known as T1R1 and T1R3), resulting from two frameshift mutations in the T1R1 exons.[fifty] Umami taste corresponds to substantial amounts of glutamate as found in meat and could have So altered the meals decision of the enormous panda.
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